Fibroblasts release low amounts of reactive oxygen intermediates (ROIs) upon contact with appropriate stimuli, which have regulatory functions in inter- and intracellular signal transduction. Ca2+/calmodulin are involved in the activation process of the ROI-generating system. A rise of intracellular Ca2+ is necessary, but not sufficient to trigger the release of ROIs. As a second signal, protein phosphorylation seems to be involved in the activation process.
CITATION STYLE
Meier, B. (1996). Regulation of the superoxide releasing system in human fibroblasts. In Advances in Experimental Medicine and Biology (Vol. 387, pp. 113–116). Springer New York LLC. https://doi.org/10.1007/978-1-4757-9480-9_15
Mendeley helps you to discover research relevant for your work.