Convenient TLC-based identification test for the crude drug "pogostemoni herba"

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Abstract

TLC and HPLC were used to identify possible chemical markers for evaluating the quality of the crude drug "Pogostemoni herba" (aerial part of Pogostemon cablin), which is a component of Kampo medicines. In addition to the reported patchouli alcohol and 2-hydroxy-6-methyl-3-(4-methylpentanoyl)-4- pyrone, three phenylethanoids were isolated from this plant material for the first time: acteoside, isoacteoside, and crenatoside. The usefulness of these compounds as indicators of the crude commercial drug under various TLC conditions was examined, and patchouli alcohol was found to give a definite spot with a reproducible Rf value. Therefore, we propose TLC of the methanol (MeOH) extract using patchouli alcohol as a marker as a convenient method for identifying the crude drug Pogostemoni herba. © 2008 The Pharmaceutical Society of Japan.

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Amakura, Y., Yoshimura, M., Mouri, C., Mikage, M., Kawahara, N., Goda, Y., & Yoshida, T. (2008). Convenient TLC-based identification test for the crude drug “pogostemoni herba.” Yakugaku Zasshi, 128(12), 1833–1837. https://doi.org/10.1248/yakushi.128.1833

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