Effect of Shark Skin Collagen on Morphologic and Biochemical Changes in a Guinea Pig Model of Osteoarthritis

  • Atsugi T
  • Nomura Y
  • Watanabe M
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Abstract

… Dunkin-Hartley guinea pigs develop a spontaneous knee OA similar to human OA [de Bri, 1995] … similarity to the condition in humans … Control (gelatin not intake) groups showed the symptoms of osteoarthritis in knee joints, that is loss of saflanin 0 staining in the area of synovial …

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Atsugi, T., Nomura, Y., & Watanabe, M. (2003). Effect of Shark Skin Collagen on Morphologic and Biochemical Changes in a Guinea Pig Model of Osteoarthritis. In Animal Cell Technology: Basic & Applied Aspects (pp. 459–463). Springer Netherlands. https://doi.org/10.1007/978-94-017-0726-8_79

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