Guess What: Chronic 13q14.3+/CD5-/CD23+ Lymphocytic Leukemia in Blood and t(11;14)(q13;q32)+/CD5 +/CD23- Mantle Cell Lymphoma in Lymph Nodes!

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Abstract

We report a case of a patient with two B-cell lymphoproliferative disorders: CD5-/CD23+ B-cell chronic lymphocytic leukemia and CD5+/CD23- mantle cell lymphoma. These disorders were diagnosed simultaneously based on flow cytometry, immunohistochemistry, fluorescence in situ hybridization, and polymerase chain reaction-based molecular studies. The B-cell lymphocytic leukemia clone predominated in the blood and bone marrow, whereas the mantle cell clone predominated in lymph nodes. © 2002 Wiley-Liss, Inc.

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Lima, M., Pinto, L., Dos Anjos Teixeira, M. D., Canelhas, Á., Mota, A., Cabeda, J. M., … Justiça, B. (2003). Guess What: Chronic 13q14.3+/CD5-/CD23+ Lymphocytic Leukemia in Blood and t(11;14)(q13;q32)+/CD5 +/CD23- Mantle Cell Lymphoma in Lymph Nodes! Cytometry Part B - Clinical Cytometry, 51(1), 41–44. https://doi.org/10.1002/cyto.b.10005

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