Nationwide surveillance of macrolide-resistant mycoplasma pneumoniae infection in pediatric patients

Abstract

We conducted nationwide surveillance to investigate regional differences in macrolide-resistant (MR) Mycoplasma pneumoniae strains in Japan. The prevalence ofMRM. pneumoniae in pediatric patients gradually increased between 2008 and 2012. Although regional differences were observed, high levels ofMRgenes were detected in all seven surveillance areas throughout Japan and ranged in prevalence from 50% to 93%. These regional differences were closely related to the previous administration of macrolides. © 2013, American Society for Microbiology. All Rights Reserved.