This paper presents our computational and measurement strategy for investigating gene networks from gene expression data using state space model and dynamic Bayesian network model with nonparametric regression. These methods are applied to gene expression data based on gene knockdowns and drug responses for generating large global maps of gene regulation which will light up the geography where drug target pathways lie down. © Springer-Verlag Berlin Heidelberg 2009.
CITATION STYLE
Miyano, S., Yamaguchi, R., Tamada, Y., Nagasaki, M., & Imoto, S. (2009). Gene networks viewed through two models. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 5462 LNBI, pp. 54–66). https://doi.org/10.1007/978-3-642-00727-9_8
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