Who do they think they are? Wnt-responsive cells reveal their family trees

Abstract

The nature of stem and progenitor cells in the mammary epithelium, and the relevance of cleared fat pad transplantation as a functional assay for them, has been thrown into doubt by recent lineage-tracking studies. Now two new studies based on tracking the progeny of Wnt-responsive cells are starting to help make sense of this fascinating problem. © 2012 BioMed Central Ltd.