Morphological Changes Induced by Instant Noodles Food on Kidney of Adult New Zealand Rabbits

Abstract

The morphological changes induced by instant noodles food on kidney was evaluated using adult newzealand rabbits. The study was carried out on twenty-two healthy male and female Rabbits, weighing between 0.7-1.5 kg for 63 days. While two rabbits died during the acclimatization period, the remaining rabbits were randomly assigned into four groups A, B, C and D and having five (n=5) each. Group A, is a control fed with normal food only, group B fed with normal food and noodles only, group C fed with normal food and seasoning only and group D fed with normal food and noodles with seasoning. The morphological changes on the kidney of the rabbits was evaluated by histopathologic examination. Histologically,Group A showed normal glomeruli, tubule and vasculatures of the kidney along with normal inner lining of the blood vessels. Group B showed moderate interstitial congestion with chronic inflammation that is perivascular. The group C shows ulceration of the intima. Group D shows deposition of hyallinised materials inside the wall of the blood vessels and also, there is narrowing of the lumen of the blood vessels and deposition of the hyalinised materials. Finally, consumption of instant noodles may lead to pathological changes in the kidney.