Penetration Rates of Formaldehyde

Abstract

Formaldehyde is one of the most rapidly penetrating fixatives used. Unfortunately, it is one of the slowest to fix tissue. This paradox was finally explained by Burnett in 1982. An fine description of the properties of formaldehyde may be found in John Kiernan's book.The penetration rate of formaldehyde in mm/hr is a variable thing. It depends on how the data is obtained. It may also vary slightly depending on tissue type. The penetration rate of formaldehyde fixatives has been extensively studied, often with conflicting results. The penetration of non-coagulating fixatives is difficult to measure.