Metal-Nucleobase Chemistry: Coordination, Reactivity, and Base Pairing

Abstract

A review, with 148 refs. The lecture is intended to provide a basis for the understanding of principles of metal-nucleic acid interactions. It will focus on topics such as the relevance of metal-nucleic acid interactions in biol., mol. biol. and medicine, coordination patterns of metal species with nucleobases, effects of metal binding on isolated nucleobases as well as oligonucleotides, with particular attention to base pairing. [on SciFinder (R)]