Bioprinting of cartilage with bioink based on high-concentration collagen and chondrocytes

31Citations
Citations of this article
55Readers
Mendeley users who have this article in their library.

Abstract

The study was aimed at the applicability of a bioink based on 4% collagen and chondrocytes for de novo cartilage formation. Extrusion-based bioprinting was used for the biofabrication. The printing parameters were tuned to obtain stable material flow. In vivo data proved the ability of the tested bioink to form a cartilage within five to six weeks after the subcutaneous scaffold implantation. Certain areas of cartilage formation were detected as early as in one week. The resulting cartilage tissue had a distinctive structure with groups of isogenic cells as well as a high content of glycosaminoglycans and type II collagen.

Cite

CITATION STYLE

APA

Beketov, E. E., Isaeva, E. V., Yakovleva, N. D., Demyashkin, G. A., Arguchinskaya, N. V., Kisel, A. A., … Kaprin, A. D. (2021). Bioprinting of cartilage with bioink based on high-concentration collagen and chondrocytes. International Journal of Molecular Sciences, 22(21). https://doi.org/10.3390/ijms222111351

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free