Natural melanogenesis inhibitors acting through the down-regulation of tyrosinase activity

212Citations
Citations of this article
328Readers
Mendeley users who have this article in their library.

Abstract

Melanogenesis is a biosynthetic pathway for the formation of the pigment melanin in human skin. A key enzyme, tyrosinase, catalyzes the first and only rate-limiting steps in melanogenesis, and the down-regulation of enzyme activity is the most reported method for the inhibition of melanogenesis. Because of the cosmetically important issue of hyperpigmentation, there is a big demand for melanogenesis inhibitors. This encourages researchers to seek potent melanogenesis inhibitors for cosmetic uses. This article reviews melanogenesis inhibitors that have been recently discovered from natural sources. The reaction mechanisms of the inhibitors on tyrosinase activity are also discussed. © 2012 by the authors.

Author supplied keywords

Cite

CITATION STYLE

APA

Chang, T. S. (2012). Natural melanogenesis inhibitors acting through the down-regulation of tyrosinase activity. Materials. https://doi.org/10.3390/ma5091661

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free