Factors affecting the rate at which a trachoma strain of Chlamydia trachomatis establishes persistent infections in mouse fibroblasts (McCoy cells)

Abstract

Chlamydiae from mouse fibroblasts (McCoy cells) persistently infected with a trachoma strain (G17) of Chlamydia trachomatis repeatedly established new persistent infections in wild McCoy cells more rapidly than did wild chlamydiae. The density and nutritional state of the host cell populations may also influence the rate of establishment of persistent infections.