In theory, the human genome is large enough to keep its roughly 20,000 genes well separated. In practice, genes are clustered; even more puzzling, in many cases both DNA strands of a protein coding gene are transcribed. The resulting natural antisense transcripts can be a blessing and curse, as many appreciate, or simply transcriptional trash, as others believe. Widespread evolutionary conservation, as recently demonstrated, is a good indicator for potential biological functions of natural antisense transcripts.See research article: http://www.biomedcentral.com/1471-2164/14/243. © 2013 Werner; licensee BioMed Central Ltd.
CITATION STYLE
Werner, A. (2013, April 12). Biological functions of natural antisense transcripts. BMC Biology. https://doi.org/10.1186/1741-7007-11-31
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