Opipramol dihydrochloride

Abstract

The title compound (systematic name: 4-{3-[2-aza-tricyclo-[9.4.0.0 3,8]penta-deca-1(15),3,5,7,11,13-hexaen-2-yl]prop-yl} -1-(2-hydroxyethyl)piperazine-1,4-diium dichloride), C23H 31N3O+·2Cl-, is the dihydro-chloride of a piperazine derivative bearing a bulky 3-(5H-dibenz[b,f] azepin-5-yl)propyl substituent. Protonation took place on both N atoms of the piperazine unit. The diazacyclohexane ring adopts a chair conformation. N - H⋯Cl, O - H⋯Cl and C - H⋯Cl hydrogen bonding as well as C - H⋯O contacts connect the components into a three-dimensional network in the crystal. Two C - H⋯π contacts are also observed. © Betz et al. 2011.