Copper-catalyzed trifluoromethylation of enol ether

Abstract

A copper-catalyzed trifluoromethylation of enol ether is developed, which provides a potential strategy for the synthesis of 2-trifluoromethyl enol ether compounds. The reaction is under mild conditions with moderate to good yields. The structures of target compounds were confirmed by NMR, IR, MS, and HRMS. © 2014 Chinese Chemical Society & SIOC, CAS.