Synthesis of 3-hydroxy-2H-iminolactones and 3-hydroxy-2H-pyrrol-2-ones from reaction between isocyanides and methyl 2-acetylacetoacetate

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Abstract

A one pot synthesis of new lactam derivatives is reported from reactions between alkyl or aryl isocyanides and methyl 2-acetylacetoacetate in good yields. ©ARKAT USA, Inc.

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Hazeri, N., Maghsoodlou, M. T., Habibi-Khorassani, S. M., & Marandi, G. (2008). Synthesis of 3-hydroxy-2H-iminolactones and 3-hydroxy-2H-pyrrol-2-ones from reaction between isocyanides and methyl 2-acetylacetoacetate. Arkivoc, 2008(14), 282–288. https://doi.org/10.3998/ark.5550190.0009.e26

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