Flavonoid compounds represent an important natural source of antiretrovirals for AIDS therapy due to their significant anti-HIV-1 activity and low toxicity. Here we propose a simple theoretical criterion to discriminate active from inactive flavonoids that is suitable for rapid in silico screening of flavonoid libraries, and selection and optimization of lead compounds with anti-HIV-1 activity. © 2006 Elsevier Ltd. All rights reserved.
CITATION STYLE
Veljkovic, V., Mouscadet, J. F., Veljkovic, N., Glisic, S., & Debyser, Z. (2007). Simple criterion for selection of flavonoid compounds with anti-HIV activity. Bioorganic and Medicinal Chemistry Letters, 17(5), 1226–1232. https://doi.org/10.1016/j.bmcl.2006.12.029
Mendeley helps you to discover research relevant for your work.