To assess myocardial fibrosis associated with muscular dystrophy, T1-mapping and extracellular volume fraction (ECV) quantification was prospectively performed using cardiovascular MR (CMR) imaging in 6 male patients with muscular dystrophy and 5 female putative carriers of Duchenne or Becker muscular dys-trophy. Five patients and all putative carriers had an elevated ECV (>29.5% for men and >35.2% for women), suggesting that ECV has a potential to detect diffuse fibrotic changes in patients and putative carriers of muscular dystrophy.
CITATION STYLE
Koyanagawa, K., Kobayashi, Y., Aikawa, T., Takeda, A., Shiraishi, H., Tsuneta, S., … Anzai, T. (2021). Myocardial t1-mapping and extracellular volume quantification in patients and putative carriers of muscular dystrophy: Early experience. Magnetic Resonance in Medical Sciences, 20(3), 320–324. https://doi.org/10.2463/mrms.bc.2020-0069
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