While adjuvant treatments of early breast cancers (BCs) had significantly improved patients' overall survival, some of them will still develop locoregional relapses and/or severe late radio-induced toxicities. Here, we propose to review how to personalize locoregional treatment by identifying patients at high and low risk of locoregional relapse, patients at risk of late radio-induced side effects. We will, therefore, discuss how to enhance BC radiosensitivity. Finally, we will address how personalized radiotherapy could be implemented in prospective clinical trials.
CITATION STYLE
Azria, D., Brengues, M., Gourgou, S., & Bourgier, C. (2018, April 5). Personalizing breast cancer irradiation using biology: From bench to the accelerator. Frontiers in Oncology. Frontiers Media S.A. https://doi.org/10.3389/fonc.2018.00083
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