Abstract
Purpose: The aim of this study was to compare functional data of different nerve-gap bridging materials evaluated in rat experiments by means of a systematic review. Materials and methods: A systematic review was conducted, searching MEDLINE, HTS and CENTRAL to identify all trials evaluating functional recovery of artificial nerve conduits in the rat model. Results: There was a trend towards a favourable outcome of conduits coated with Schwann-cells compared to the plain synthetics. Histomorphometry, electrophysiology and muscle-weight correlated poorly with functional outcome. Conclusion: Schwann-cell coated conduits showed promising results concerning functional recovery. Further standardization in outcome reporting is encouraged. © 2009 Sinis et al; licensee BioMed Central Ltd.
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
Cite
CITATION STYLE
Sinis, N., Kraus, A., Tselis, N., Haerle, M., Werdin, F., & Schaller, H. E. (2009). Functional recovery after implantation of artificial nerve grafts in the rat- a systematic review. Journal of Brachial Plexus and Peripheral Nerve Injury, 4(1), 19. https://doi.org/10.1186/1749-7221-4-19
Readers over time
Readers' Seniority
Readers' Discipline
