Scopolamine, morphine, and brain-stem auditory evoked potentials in awake monkeys

Abstract

The effects of scopolamine and morphine sulfate on brain-stem auditory evoked potentials (BAEPs) were studied in 10 rhesus (Macaca mulatta) monkeys. Study drugs were given intravenously to unanesthetized animals and BAEPs recorded at 3-min and 30-min intervals after administration of 0.1 mg/kg and 0.32 mg/kg of scopolamine and 15 min after administration of 3.2 mg/kg morphine at the end of the experiment. No significant change in either latency or amplitude of different components of BAEPs was observed.