Abstract
The GATA family of transcription factors consists of six proteins (GATA1-6) which are involved in a variety of physiological and pathological processes. GATA1/2/3 are required for differentiation of mesoderm and ectoderm-derived tissues, including the haematopoietic and central nervous system. GATA4/5/6 are implicated in development and differentiation of endoderm- and mesoderm-derived tissues such as induction of differentiation of embryonic stem cells, cardiovascular embryogenesis and guidance of epithelial cell differentiation in the adult.
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CITATION STYLE
Lentjes, M. H. F. M., Niessen, H. E. C., Akiyama, Y., Bruïne, D. A. P., Melotte, V., & Engeland, M. V. A. N. (2016, March 8). The emerging role of GATA transcription factors in development and disease. Expert Reviews in Molecular Medicine. Cambridge University Press. https://doi.org/10.1017/erm.2016.2
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