The results on the stability of glycolytic metabolic networks in different cells

Abstract

Evolutionary forces will affect the structure of metabolic networks and their dynamic behaviors. To examine this hypothesis, in this work we investigate the relationship between the complexity of the metabolic glycolytic networks and the stability of the networks in different cells. By deriving the stoichiometrix from the FBA methods, we develop the models for Sce, Dmgr, Dsmi and Pic in fungi. Based on these models, we analyze the stability of the networks. The results show that the metabolic networks are more complicated with more stable ones. © 2009 ICST Institute for Computer Sciences, Social Informatics and Telecommunications Engineering.