Plasmablastic lymphoma (PBL) clinical descriptions are scarce from sub-Saharan Africa (SSA) where both HIV and EBV are highly endemic. We identified 12 patients with pathologically confirmed PBL from a prospective cohort in Lilongwe, Malawi. Median age was 46 (range 26-71), seven (58%) were male, and six (50%) were HIV-positive. Eight patients were treated with CHOP and four with a modified EPOCH regimen. One-year overall survival was 56% (95% CI 24-79%), without clear differences based on HIV status. PBL occurs in Malawi in HIV-positive and HIV-negative individuals and can be treated successfully with curative intent, even in a low-resource setting in SSA.
CITATION STYLE
Zuze, T., Painschab, M. S., Seguin, R., Kudowa, E., Kaimila, B., Kasonkanji, E., … Gopal, S. (2018). Plasmablastic lymphoma in Malawi. Infectious Agents and Cancer, 13(1). https://doi.org/10.1186/s13027-018-0195-4
Mendeley helps you to discover research relevant for your work.