Traditionally, the family of G protein-coupled receptors (GPCRs) has been divided into “classical” GPCRs and olfactory (or gustatory) GPCRs. The classical GPCRs comprise receptors for all neurotransmitters and hormones, displaying a vast chemical diversity among their natural ligands. Odorant receptors are believed to bind volatile molecules, but the mechanisms of ligand binding in this group are less well-understood.
CITATION STYLE
Reinscheid, R. K., & Civelli, O. (2005). De-Orphanizing GPCRs and Drug Development. In Contemporary Clinical Neuroscience (pp. 389–401). Springer Nature. https://doi.org/10.1007/978-1-59259-919-6_18
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