The mechanisms underlying integrin-dependent signalling are a topic of continued study. Endocytosed integrins are now shown to drive assembly of signalling complexes on the cytoplasmic face of endocytic membranes to promote cancer cell survival and increase metastatic capacity following cell detachment.
CITATION STYLE
Rainero, E., & Norman, J. C. (2015). Endosomal integrin signals for survival. Nature Cell Biology, 17(11), 1373–1375. https://doi.org/10.1038/ncb3261
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