Lymphocyte and neutrophil to lymphocyte ratio do not predict mortality in hip fracture patients

Abstract

Our study aimed to assess whether admission hemoglobin, lymphocyte count and neutrophil to lymphocyte ratio (N/R) can predict 1-year survival in patients with hip fractures. In the study, data from 54 patients with femoral neck fractures, 119 with trochanteric fractures respectively 24 with subtrochanteric fractures was analyzed. All the included patients were older than 55 years and were followed up to 2 years or until the decease occurred. The following parameters were recorded in patients with femoral neck, trochanteric respectively subtrochanteric fractures: average age: 76; 79.7 respectively 73.3 years; male to female ratio: 1:2.86; 1:3.1 respectively 1:2; average hemoglobin at admission: 13.13, 11.56 respectively 11.81; average lymphocyte count: 1.69; 1.7 respectively 1.75. At the logistic regression model built having the death as outcome and the lymphocytes respectively the N/L as predictors, we did notfound any significant associations in neither of the groups (p values of 0.837, 0.171 and 0.162 for lymphocyte and 0.920, 0.764 and 0.168 for N/ L respectively). When age, gender and hemoglobin at admittance were accounted for, only for fractures of the trochanteric region age was predictive of survival with p<0.001. Our study showed no prediction for survival of hip fracture patients by using perioperatively collected total lymphocyte count and neutrophil to lymphocyte ratio.