Eficacia analgésica de una combinación utilizada en perras sometidas a ovariohisterectomía

Abstract

Postoperative control of pain reduces morbidity and mortality, allowing a shorter hospitalization and an early return to ambulatory state and normal behavior. Evaluation of pain is based on probability, physiological parameters and behavioral responses. The objective of this work was to determine the intraoperative effect of an analgesic infusion, evaluating probable cardiorespiratory as well as rectal temperature variations, and to establish quality and recovery times. Fifteen female dogs were submitted to ovariohysterectomy to avoid procreation, administering an analgesic combination protocol (tramadol, lidacaine, xilacine and ketamine). The premedication was performed with tramadol and xilacine, both by subcutaneous administration; tramadol was administered 30 minutes before xilacine. Induction was carried out with propofol and diazepam. Analgesic combination perfusion began before endotracheal intubation. Then, isoflurane was administered in an initial concentration of 3%, varying according to the requirement of each patient (1.5-3%). Oxygen was provided at a rate of 20 ml/kg/minute. There were no significant changes in the rectal temperature, heart rate nor electrocardiographic monitoring, with some variations in respiratory rate and blood pressure, which were evaluated in 8 different times, initiating 5 minutes before the anesthetic premedication. Towards the middle of the assay, respiratory rate was recorded in the lower limits. Blood pressure showed initial elevations in concordance with the moments of highest nociceptive stimulation. It is concluded that the analgesic combination allowed an adequate analgesia without causing haemodynamic and respiratory relevant alterations.