In the last years, life-threatening fungal diseases have increased signifi cantly, due to the rising number of human individuals susceptible to fungal infections, which are in part complicated by the emergence of antifungal drug-resistant pathogens. Among yeasts, Candida albicans and Candida glabrata are the most common organisms responsible for invasive fungal diseases. The molecular detection of echinocandin resistance in Candida species may represent a useful means of monitoring the incidence of clinical isolates with antifungal resistance-associated gene alterations. Here, we describe the current methods that enable researchers and/or clinical microbiologists to accurately detect echinocandin-resistant isolates of C. albicans and C. glabrata .
CITATION STYLE
Posteraro, B., Vella, A., de Carolis, E., & Sanguinetti, M. (2017). Molecular detection of resistance to echinocandins. In Methods in Molecular Biology (Vol. 1508, pp. 413–421). Humana Press Inc. https://doi.org/10.1007/978-1-4939-6515-1_23
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