Adenosine-stress dynamic myocardial perfusion imaging using 128-slice dual-source CT: Optimization of the CT protocol to reduce the radiation dose

39Citations
Citations of this article
20Readers
Mendeley users who have this article in their library.
Get full text

Abstract

The aim of this study was to compare the radiation dose and image quality of different adenosine-stress dynamic myocardial perfusion CT protocols using a 128-slice dual-source computed tomography (DSCT) scanner. We included 330 consecutive patients with suspected coronary artery disease. Protocols employed the following dynamic scan parameters: protocol I, a 30-s scan with a fixed tube current (FTC, n = 172); protocol II, a 30-s scan using an automatic tube current modulation (ATCM) technique (n = 108); protocol III, a 14-s scan using an ATCM (n = 50). To determine the scan interval for protocol III, we analyzed time-attenuation curves of 26 patients with myocardial perfusion who had been scanned using protocol I or II. The maximum attenuation difference between normal and abnormal myocardium occurred at 18.0 s to 30.3 s after initiation of contrast injection. Myocardial perfusion images of FTC and ATCM were of diagnostic image quality based on visual analysis. The mean radiation dose associated with protocols I, II, and III was 12.1 ± 1.6 mSv, 7.7 ± 2.5 mSv, and 3.8 ± 1.3 mSv, respectively (p < 0.01). Use of a dose-modulation technique and a 14-s scan duration for adenosine-stress CT enables significant dose reduction while maintaining diagnostic image quality. © 2012 Springer Science+Business Media Dordrecht.

Cite

CITATION STYLE

APA

Kim, S. M., Kim, Y. N., & Choe, Y. H. (2013). Adenosine-stress dynamic myocardial perfusion imaging using 128-slice dual-source CT: Optimization of the CT protocol to reduce the radiation dose. International Journal of Cardiovascular Imaging, 29(4), 875–884. https://doi.org/10.1007/s10554-012-0138-x

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free