Serotonin syndrome in asymptomatic huntington’s disease

Abstract

Serotonin syndrome is a rare and serious condition most often resulting from iatrogenic insult; the prescriber’s pen is sometimes the most poisonous. Here, Dr Haffenden and Dr Patel discuss a complex case of serotonin syndrome in a patient with genetically proven, but not yet symptomatic, Huntington’s disease and chronic renal impairment. A screening process is proposed to recognise the multitude of precipitating factors, which aligned in this case, and could either alter our prescribing or expedite recognition.