Development of IMRT treatment planning system

Abstract

Development experience of IMRT treatment planning system focused on the objective function and optimization method was presented. Beamlet based fast dose calculation algorithm was implemented to calculate Dij matrix and a quadratic objective function based on DVH volume constraint was implemented. It was solved with a steepest descent method and the optimized intensity map could be obtained. For the verification of the algorithm, several test phantoms and sample plan was tested. As a result, all the dose volume histogram satisfied the treatment prescriptions and the high dose regions maintained the shape of PTV and did not violated OAR. In conclusion, it could incorporate clinical treatment prescriptions into optimization module and generate corresponding dose distributions within reasonable time. © 2009 Springer-Verlag.