SP529PERITONEAL ULTRAFILTRATION WITH A STABLE GLUCOSE CONCENTRATION USING THE CARRY LIFE® UF SYSTEM

Abstract

INTRODUCTION AND AIMS: Carry Life® System UF (CLS UF) is a new portable device intended to achieve a gentle and efficient peritoneal ultrafiltration in patients requiring fluid removal. The therapeutic concept is that a stable glucose concentration at an adequate level will achieve a more efficient ultrafiltration compared to standard PD methods. A stable glucose concentration is obtained by administering glucose to the intraperitoneal fluid throughout the treatment, at a rate which compensates for glucose absorption. The device administers glucose via a standard PD catheter, and consists of two separate parts, the cycler and line set. During treatment, a portion (~180ml) of the intraperitoneal fluid (IP) is transferred into the device four times per hour and 20% glucose is added and diluted before the fluid is returned to the patient. The aim was to perform a feasibility study with the CLS UF device in order to evaluate 1) the ability of the device to maintain the intraperitoneal glucose concentration 2) ultrafiltration and total fluid output and 3) patient tolerability.