Chronic kidney disease (CKD) is a very common chronic non-communicable disease. Phosphate and calcium metabolism disorders are one of the most common features of CKD. Sevelamer carbonate is the most widely used non-calcium phosphate binder. Gastrointestinal (GI) injury associated with sevelamer use is a documented adverse effect but is underrecognized as a cause of gastrointestinal symptoms in patients with CKD. We report a case of a 74-year-old woman taking low-dose sevelamer with serious gastrointestinal adverse effects causing colon rupture and severe gastrointestinal bleeding.
CITATION STYLE
Fistrek Prlic, M., Jelakovic, M., Brinar, M., Grgic, D., Romic, I., Marusic, Z., … Krznaric, Z. (2023). Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding. Frontiers in Medicine, 10. https://doi.org/10.3389/fmed.2023.1097469
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