A bioactive spirolactone iridoid and triterpenoids from Himatanthus sucuuba

Abstract

Himatanthus sucuuba is an Amazonian tree with abundant, yet conflicting ethnobotanical information. Investigation of the polar and non-polar constituents led to the isolation of plumericin, a bioactive spirolactone iridoid, and four known pentacylic triterpenes: lupeol acetate, lupeol cinnamate, lupeol β-phenyl propionate, and α-amyrin cinnamate.