Multiplex PCR for diagnosis of AIDS-related central nervous system lymphoma and toxoplasmosis

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Abstract

A nested multiplex PCR assay was designed for the simultaneous detection of Epstein-Barr virus and Toxoplasma gondii DNA from the cerebrospinal fluid of AIDS patients. T. gondii DNA was detected in 8 of 8 patients with Toxoplasma encephalitis and in 0 of 6 patients without toxoplasmosis, and Epstein-Barr virus DNA was found in 9 of 14 patients with central nervous system lymphoma and in 2 of 38 patients without disease.

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APA

Roberts, T. C., & Storch, G. A. (1997). Multiplex PCR for diagnosis of AIDS-related central nervous system lymphoma and toxoplasmosis. Journal of Clinical Microbiology, 35(1), 268–269. https://doi.org/10.1128/jcm.35.1.268-269.1997

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