Bone mineral density in men with and without the metabolic syndrome

Abstract

The objective of this study was to measure bone mineral density BMD in middle-aged men with and without the metabolic syndrome according to the International diabetes federation IDF definition from 2005. We studied 80 men mean age: 51.9 ± 9.0 y, mean body mass index BMI: 32.0 ± 1.7 k/gm2 with and 92 men without the metabolic syndrome mean age: 52.6 ± 15.1 y, mean BMI: 24.9 ± 2.8 k/gm2. Height cm, weight kg, waist circumference cm and blood pressure were measured. Fasting plasma glucose FPG and blood lipids were determined. BMD at the lumbar spine and total hip was measured by dual X-ray absorptiometry on a Hologic QDR 4500 bone densitometer. In men around 59.3 had a waist circumference > 94 cm abdominal obesity. Among them 58.7 showed abnormal BP values. Around 30.7 had FPG ≥ 5.6 mmolL and 22.7 had low high density lipoprotein HDL-cholesterol and 36.6 had hypertriglyceridemia. In men with the metabolic syndrome, mean lumbar spine BMD was 0.986 ± 0.210 g/cm2 and total hip BMD 1.012 ± 0.209 g/cm2. The corresponding values in men without this syndrome were 0.934 ± 0.179 g/cm2 and 0.894 ± 0.189 g/cm2, respectively. The inter-group BMD difference reached statistical significance only at the hip p 0.039. Respectively, the prevalence of osteoporosis at the central sites was significantly higher in men without the metabolic syndrome MS 13.2 versus 20.8, p 0.03. Our data confirmed the trend for higher BMD in the studied men with the metabolic syndrome. © 2009 Informa UK Ltd. All rights reserved.