A method and system to simulate human electrophysiological activity

Abstract

Accurate electrophysiological diagnosis relies on high precision and well calibrated instruments. A method to simulate the human electrophysiological activity is proposed and a simulation system is developed, as a calibration tool for electrophysiological inspectors. The system performance is tested by calibrating the amplitude and the latency of a commercial visual electrophysiological instrument. Several typical simulating signals are tested. The minimum amplitude of the simulating signal can be lower than 1 μV. Measurement errors and uncertainties are calculated. The traceability of the measurement results to metrological standards is also demonstrated. It is proved by experimental results that the system can generate simulating signals with different waveforms and variable parameters and it can be used to simulate the human visual electrophysiological activities. With simple modifications to the simulation system, it can also be used to calibrate other electrophysiological inspectors.