Autosomal dominant polycystic kidney disease: genetics, epidemiology, and treatment

  • Reed-Gitomer B
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Abstract

... All renal epithelial cells (except for collecting duct intercalated cells) possess a single primary cilium . ... 25 It seems that primary cilia act as mechanosensors, since flow-induced bending leads to ... This appears to be modulated via the ciliary polycystin complex, with PC-2 mediating ...

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Reed-Gitomer, B. (2014). Autosomal dominant polycystic kidney disease: genetics, epidemiology, and treatment. Advances in Genomics and Genetics, 173. https://doi.org/10.2147/agg.s53161

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