Successful fertility-sparing surgery and chemotherapy for stage IC3 ovarian cancer with the postoperative use of the traditional Japanese herbal formulation hachimijiogan: A case report

Abstract

Case: A 32-year old, unmarried, nulligravida woman was diagnosed as having ovarian cancer stage IC3. The patient received six cycles of carboplatin and paclitaxel every 4 weeks after surgery. She was given a gonadotropin-releasing hormone agonist as an ovarian safeguard while receiving treatment with anticancer agents. Outcome: After treatment with the traditional Japanese herbal formulation hachimijiogan and oral contraceptives, the patient spontaneously became pregnant and gave birth to a healthy baby at 40 gestational weeks. Conclusion: A hachimijiogan treatment may be effective for treating decreased ovarian function following chemotherapy.