Some Aspects of the Biological Role of Adenosine 3',5'-monophosphate (Cyclic AMP)

  • SUTHERLAND E
  • ROBISON G
  • BUTCHER R
N/ACitations
Citations of this article
39Readers
Mendeley users who have this article in their library.

Abstract

Cyclic AMP (adenosine 3',5'-monophosphate or cyclic adenylate) has now been established as a second messenger mediating many of the effects of a variety of hormones. Several of the metabolic effects mediated by cyclic AMP are discussed, and it is suggested that certain other ("functional" or "mechanical") hormonal effects may be similarly mediated. In particular, the evidence presented supports the hypothesis that the positive inotropic response to the catecholamines is mediated by cyclic AMP. Although knowledge of the biological role of cyclic AMP has not been widely applied clinically, sufficient knowledge has now accumulated to make research in this area desirable.

Cite

CITATION STYLE

APA

SUTHERLAND, E. W., ROBISON, G. A., & BUTCHER, R. W. (1968). Some Aspects of the Biological Role of Adenosine 3’,5’-monophosphate (Cyclic AMP). Circulation, 37(2), 279–306. https://doi.org/10.1161/01.cir.37.2.279

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free