Abstract
1-(S)-Hydroxy-2-(S, S)-valylamido-cyclobutane-l-acetic acid was isolated from a fermentation broth of an unidentified Streptomyces species X-1092. The structure was determined by single crystal X-ray diffraction analysis of the p-bromophenylcarbamyl derivative. The substance inhibits the growth of gram-positive microorganisms in a chemically defined medium but growth inhibition is partially reversed by L-cysteine. © 1974, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
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CITATION STYLE
Pruess, D. L., Scannell, J. P., Blount, J. F., Ax, H. A., Kellett, M., Williams, T. H., & Stempel, A. (1974). Antimetabolites produced by microorganisms. XI. 1-(S)-hydroxy-2-(S, S)-valylamido-cyclobutane-1-acetic acid. The Journal of Antibiotics, 27(10), 754–759. https://doi.org/10.7164/antibiotics.27.754
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