Application of Bombyx mori Silk Fibroin as a Biomaterial for Vascular Grafts

Abstract

Although silk is known primarily as a textile material, silk fibroin from silkworm (Bombyx mori) has been used as a biomedical suture material for centuries. This review focuses on the application of B. mori silk fibroin to biomaterials, particularly vascular grafts with small diameter (<6 mm). The benefits of silk fibroin for use as a biomaterial are emphasized, especially with respect to the development of silk vascular grafts.