Detection of Fatty Acids Profile in Human Saliva with Special Reference to Ovulation

Abstract

Human saliva was analyzed by Gas-Chromatography (GC) for fatty acids study throughout menstrual cycle. The fatty acid profiles from preovulatory, ovulatory and postovulatory phase's sample were compared to establish any qualitative and quantitative differences that might have potential value in detection of ovulation in women. In the present study, 17 different types of fatty acids were identified. The fatty acids resembling as Oleic acid, Palmitic acid and acetic acid were comparatively higher in concentration than the other fatty acids. These three fatty acid were mostly present in ovulatory phase, to be higher when compared to follicular and luteal phases of menstrual cycle bear out the cyclic fluctuations in lipid levels do occur under the influence of both endogenous and exogenous sex hormones. The results imply that the variation in the fatty acids is unswervingly/ obliquely correlated to the phase of menstrual cycle.