Using conditional deletion of endogenously expressed Piezo2 or ectopic expression of Piezo1 in primary somatosensory neurons, Zhang et al. find that mechanically activated Piezo channels can mediate touch and proprioception as well as indirectly suppress acute mechanical pain responses in mice.
CITATION STYLE
Zhang, M., Wang, Y., Geng, J., Zhou, S., & Xiao, B. (2019). Mechanically Activated Piezo Channels Mediate Touch and Suppress Acute Mechanical Pain Response in Mice. Cell Reports, 26(6), 1419-1431.e4. https://doi.org/10.1016/j.celrep.2019.01.056
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