Sezary syndrome

Abstract

For many years the definition of Sezary syndrome has been unsettled. Clinically, Sezary syndrome is indistinguishable from erythrodermic mycosis fungoides (MF). The decision as to whether the patient has erythrodermic MF or Sezary syndrome depends on whether or not the blood is involved by the neoplastic process. If there is positive evidence of blood involvement, the patient is considered to have Sezary syndrome. If the evidence is not conclusive, a diagnosis of erythrodermic MF is made.