The objectives of a safety pharmacology study of the respiratory system are to determine whether a drug has the potential to produce a change in respiratory function and to establish whether this change is a liability. Such changes can result from either the primary or secondary pharmacological properties of a drug or from organ dysfunction resulting from the toxicological properties of a drug.
CITATION STYLE
Murphy, D. J. (2013). Respiratory function assays in safety pharmacology. In Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays, Second Edition (pp. 185–198). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-25240-2_6
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