Generation of Cardiomyocytes Derived from Mouse ESC in a Scale-up System

  • Niebruegge S
  • Ebelt H
  • Jungblut M
  • et al.
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Abstract

The cultivation of embryonic stem, cells (ES cells) in a standard stirred tank bioreactor makes it possible to generate large numbers of therapeutically usable cells such as cardiomyocytes. We have used this technique to expand genetically engineered ES cells transfected with a fusion gene that allows an efficient enrichment of cardiomyocytes via antibiotic addition

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Niebruegge, S., Ebelt, H., Jungblut, M., Baer, H., Schroeder, M., Zweigerdt, R., … Lehmann, J. (2007). Generation of Cardiomyocytes Derived from Mouse ESC in a Scale-up System. In Cell Technology for Cell Products (pp. 191–195). Springer Netherlands. https://doi.org/10.1007/978-1-4020-5476-1_31

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