Pregabalin Versus Acetaminophen for a Treatment of Chronic Neuropathic Pain on Extremities after Cervical Surgery: A Prospective Randomized, Open-Label Preliminary Study

Abstract

INTERVENTION: oral administration of pregabalin oral administration of acetaminophen, CONDITION: CSM OPLL, PRIMARY OUTCOME: JOA score, JOACMEQ, NDI, VAS for pain; These items will be evaluated until 8 weeks after treatment., INCLUSION CRITERIA: 1:surgery for cervical degeneration such as spondylosis, herniation, or ossification of the posterior longitudinal ligament; 2:diagnosis of neuropathic pain and/or numbness of the upper and/or lower extremities lasting for at least 3 months after the operation; 3: Neuropathic Pain Screening Question-naire (painDETECT) score greater than or equal to 6 and visual analog scale (VAS) of neuropathic pain of the upper and/or lower extremities greater than 40mm;